The purposes of this study were to: 1) identify African immigrant mothers’ views of perinatal mental health and to identify predictors of those views, and 2) identify African immigrant mothers’ views regarding perinatal mental health screening and to determine factors associated with those views. A survey conducted across Alberta (predominantly in Calgary, Edmonton and Lethbridge) showed African immigrant mothers’ knowledge of postnatal mental health is high, but there is less knowledge on prenatal mental health and its effect on child development. There was also high acceptability of universal perinatal mental health screening.